MAGUKs: multifaceted synaptic organizers
نویسندگان
چکیده
منابع مشابه
Secreted factors as synaptic organizers.
A critical step in synaptic development is the differentiation of presynaptic and postsynaptic compartments. This complex process is regulated by a variety of secreted factors that serve as synaptic organizers. Specifically, fibroblast growth factors, Wnts, neurotrophic factors and various other intercellular signaling molecules are proposed to regulate presynaptic and/or postsynaptic different...
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Synaptogenesis is thought to be mediated by cell adhesion proteins, which induce the initial contact between an axon and its target cell and subsequently recruit and organize the presynaptic and postsynaptic protein machinery required for synaptic transmission. A new study by Linhoff and colleagues in this issue of Neuron identifies adhesion proteins of the LRRTM family as novel synaptic organi...
متن کاملOrganizers
Program Committee Liz Bradley (University of Colorado, Boulder, USA) Gully Burns (USC Information Sciences Institute, USA) Ishanu Chattopadhyay (Cornell University, USA) Tim Clark (Harvard University, USA) Anita de Waard (Elsevier) Michel Dumontier (Stanford University, USA) Saso Dzeroski (Jozef Stefan Institute, Slovenia) Susan Epstein (e CUNY Graduate School and Hunter College, USA) Ashok Go...
متن کاملPSD-95-like membrane associated guanylate kinases (PSD-MAGUKs) and synaptic plasticity.
Activity-dependent modification of excitatory synaptic transmission is a fundamental mechanism for developmental plasticity of the neural circuits and experience-dependent plasticity. Synaptic glutamatergic receptors including AMPA receptors and NMDA receptors (AMPARs and NMDARs) are embedded in the postsynaptic density, a highly organized protein network. Overwhelming data have shown that PSD-...
متن کاملOrganizers
Program Committee John Collins (University of Minnesota, USA) Shaheen Fatima (University of Loughborough, UK) Enrico Gerding (University of Southampton, UK) Maria Gini (University of Minnesota, USA) Amy Greenwald (Brown University, USA) Gordan Jezic (University of Zagreb, Croatia) Patrick R. Jordan (Microso, USA) Wolf Ketter (RSM Erasmus University, Netherlands) Christopher Kiekintveld (Univer...
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ژورنال
عنوان ژورنال: Current Opinion in Neurobiology
سال: 2017
ISSN: 0959-4388
DOI: 10.1016/j.conb.2017.01.006